Lessons learned while traversing the welwitindolinone alkaloids obstacle course

Vikram Bhat, The University of Chicago
James A. MacKay, The University of Chicago
Viresh H. Rawal, The University of Chicago


We recount several unexpected results observed in the course of our work toward the synthesis of welwitindolinone alkaloids. The surprising results provide an opportunity to refine one's understanding of the interplay between chemical structure and reactivity. © 2011 Elsevier B.V. All rights reserved.