Document Type



Summer 2022

Academic Department

Chemistry and Biochemistry

Faculty Advisor(s)

Dr. Lauren Toote


According to a recent survey by the United States Environmental Protection Agency (EPA), there are between 6 to 10 million lead (Pb2+) service lines in the country. Consumption of lead can cause brain and kidney damage. Our goal is to create a simple, inexpensive paper-based assay to make lead testing accessible. Lateral flow assays (LFAs) are rapid tests (5-30 mins) used to detect or quantify analytes in mixtures. Each LFA has a control line and a test line(s). The control line ensures the test is working. In our test, the control line is composed of neutral red polymer nanoparticles, which are pH sensitive, resulting in a colorimetric change when a water sample is added. Nanoparticles with a size of 180 nm were synthesized and analyzed using UV-Vis and DLS. The control line signal on the lateral flow assay was best five minutes after tap water was added.


Scholarship, Creative Arts, and Research Project (SCARP)

Included in

Chemistry Commons



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